Send to:

Choose Destination
See comment in PubMed Commons below
Br J Ophthalmol. 2012 Nov;96(11):1395-8. doi: 10.1136/bjophthalmol-2011-301353. Epub 2012 Aug 24.

Long-term visual outcomes following lens-sparing vitrectomy for retinopathy of prematurity.

Author information

  • 1Alkek Eye Center, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.



To describe the long-term outcomes of lens-sparing vitrectomy (LSV) for retinopathy of prematurity (ROP).


Single-centre retrospective case series of eyes that underwent LSV for ROP between 1998 and 2005 and had a follow-up of at least 5 years. The primary outcome was the mean visual acuity, and secondary outcomes were the proportion of eyes without functional vision, proportion of eyes with anatomic success, proportion of Stage 4A eyes with vision better than 20/400, proportion of Stage 4B eyes with vision better than 20/800.


Thirty-seven eyes of 30 patients (mean age at last follow-up: 7.1 years) were included in the study, while an additional 23 patients had been lost to follow-up and were not included in the study. Of eyes that underwent LSV for Stage 4A or 4B: 63% had measurable visual acuity (mean logMAR 0.92 for Stage 4A, 1.63 for Stage 4B), 19% had form vision, but neurological comorbidities precluded visual acuity measurement, and the remaining 18% had light perception or no light perception.


While most eyes that underwent LSV for Stage 4A or 4B ROP maintain useful vision with long-term follow-up, approximately one-fifth of eyes had no functional vision, and in a further fifth, vision could not be measured due to severe neurological impairment.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk