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Blood. 2012 Aug 23;120(8):1540-1. doi: 10.1182/blood-2012-06-433979.

What T cells see in WT-1.

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  • 1MD Anderson Cancer Center, USA.

Abstract

The Wilms tumor protein, WT-1, is a widely recognized tumor antigen that is aberrantly expressed in myeloid and lymphoid leukemia and in this issue of Blood, Doubrovina et al report the most extensive catalog heretofore of HLA-restricted immunogenic peptides derived from WT-1, which are recognized by CD8 and CD4T cells.

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PMID:
22918422
[PubMed - indexed for MEDLINE]
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