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Sultan Qaboos Univ Med J. 2012 Aug;12(3):360-3. Epub 2012 Jul 15.

Nodular Melanoma Mimicking Keratoacanthoma: Lessons to learn.

Author information

  • 1Departments of Family Medicine.

Abstract

A 67-year-old man of Chinese descent presented with a painless nodular lesion that had been present on his right forearm for the previous 3 months. A single, well-defined, dome-shaped, firm nodule with a central keratin plug surrounded by erythema was noted. Keratoacanthoma with secondary bacterial infection was suspected and the patient underwent an excision biopsy. Biopsy of the nodule and immunohistochemical staining supported a diagnosis of nodular malignant melanoma. It should be noted both that nodular malignant melanoma may present with a wide variety of clinical appearances, and that the lack of melanin pigment in nodular malignant melanoma may hinder the diagnosis of this aggressive tumour.

KEYWORDS:

Case report; Keratoacanthoma; Malaysia; Malignant melanoma; Melanoma

PMID:
22912931
[PubMed]
PMCID:
PMC3413629
Free PMC Article
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