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BMC Biol. 2012 Aug 21;10:75. doi: 10.1186/1741-7007-10-75.

Different noses for different mice and men.

Author information

  • 1The Rockefeller University, New York, NY 10065, USA. andreas.keller@rockefeller.edu

Abstract

Chemosensory receptor genes encode G protein-coupled receptors with which animals sense their chemical environment. The large number of chemosensory receptor genes in the genome and their extreme genetic variability pose unusual challenges for understanding their evolution and function. Two articles in BMC Genomics explore the genetic variation of chemosensory receptor gene repertoires in humans and mice and provide unparalleled insight into the causes and consequences of this variability.

PMID:
22908960
[PubMed]
PMCID:
PMC3424162
Free PMC Article
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