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J Cataract Refract Surg. 2012 Oct;38(10):1724-33. doi: 10.1016/j.jcrs.2012.05.032. Epub 2012 Aug 15.

Impact of corneal aberrations on through-focus image quality of presbyopia-correcting intraocular lenses using an adaptive optics bench system.

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  • 1Flaum Eye Institute, University of Rochester, Rochester, NY 14624, USA.

Abstract

PURPOSE:

To measure the impact of corneal aberrations on the through-focus image quality of presbyopia-correcting intraocular lenses (IOLs) using an adaptive optics IOL metrology system.

SETTING:

Flaum Eye Institute, University of Rochester, Rochester, New York, USA.

DESIGN:

Experimental study.

METHODS:

An adaptive optics IOL metrology system comprising a model eye, wavefront sensor, deformable mirror, and an image-capturing device acquired through-focus images of a letter chart with 3.0 mm and 5.0 mm pupil diameters. The system was used to induce corneal astigmatism and higher-order aberrations (HOAs) in previously measured pseudophakic presbyopic eyes. A single-optic accommodating IOL (Crystalens HD (HD500), an apodized (Restor +3.0 diopter [D] SN6AD1) and full-aperture (Tecnis ZM900) diffractive multifocal IOL, and a monofocal IOL (Acrysof SN60AT) were evaluated. Image quality was quantified using the correlation-coefficient image-quality metric.

RESULTS:

The single-optic accommodating IOL and monofocal IOL performed similarly; however, with a 3.0 mm pupil, the former had better intermediate (1.50 D) image quality. The multifocal IOLs had bimodal through-focus image quality trends. Corneal astigmatism reduced through-focus image quality and depth of focus with all IOLs; however, the multifocal IOLs had the most severe decline in depth of focus. Ocular spherical aberration had the strongest impact on image quality when typical pseudophakic corneal HOAs were present.

CONCLUSIONS:

The uncorrected corneal astigmatism and HOAs in pseudophakic eyes significantly affected through-focus performance of presbyopia-correcting IOLs. Although multifocal IOLs significantly increased depth of focus, this benefit diminished when more than 0.75 D astigmatism remained uncorrected. Residual ocular spherical aberration had a significant effect on image quality in the presence of other corneal HOAs.

Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

PMID:
22902188
[PubMed - indexed for MEDLINE]
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