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Cell. 2012 Aug 17;150(4):667-8. doi: 10.1016/j.cell.2012.07.027.

Contraception for men: a breakthrough new approach.

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  • Department of Medicine, University of Washington, Seattle, WA 98195, USA. wbremner@uw.edu


There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular bromodomain without apparent adverse effect on the organism or offspring.

Copyright © 2012 Elsevier Inc. All rights reserved.

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