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Clin Nucl Med. 2012 Sep;37(9):897-8. doi: 10.1097/RLU.0b013e31825b2042.

18F-FDG PET/CT diagnosis of vagus nerve neurolymphomatosis.

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  • 1Department of Diagnostic Radiology, Queen Mary Hospital, University of Hong Kong, Hong Kong.


A 62-year-old woman was in remission from previously treated stage IV diffuse large B-cell lymphoma with cranial involvement. She presented with new-onset hoarseness of voice and choking; MRI of the brain showed disease recurrence in the left cavernous sinus. She was subsequently referred for F-FDG PET/CT with contrast for further evaluation of lymphomatous recurrence. F-FDG PET/CT not only revealed hypermetabolic activity in the left cavernous sinus correlating to the MRI findings but also showed an interesting manifestation explaining the patient's hoarseness of voice, being neurolymphomatosis along the left vagus nerve.

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