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J Bacteriol. 2012 Sep;194(17):4745. doi: 10.1128/JB.00956-12.

Complete genome sequence of Methanomassiliicoccus luminyensis, the largest genome of a human-associated Archaea species.

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  • 1Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Aix Marseille Université, UMR CNRS 7278, IRD 198, INSERM 1095, Faculté de Médecine, Marseille, France.


The present study describes the complete and annotated genome sequence of Methanomassiliicoccus luminyensis strain B10 (DSM 24529(T), CSUR P135), which was isolated from human feces. The 2.6-Mb genome represents the largest genome of a methanogenic euryarchaeon isolated from humans. The genome data of M. luminyensis reveal unique features and horizontal gene transfer events, which might have occurred during its adaptation and/or evolution in the human ecosystem.

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