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AIDS. 2012 Oct 23;26(16):2110-2. doi: 10.1097/QAD.0b013e328358daea.

Thalidomide for steroid-dependent immune reconstitution inflammatory syndromes during AIDS.

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  • 1Infectious Diseases Department, Montpellier University Hospital, Montpellier, France.

Abstract

Management of relapsing or refractory immune reconstitution inflammatory syndromes (IRISs) despite corticosteroid therapy is yet to be defined. We describe three HIV-infected patients with corticosteroid-dependent and life-threatening paradoxical immune reconstitution inflammatory syndrome for whom thalidomide treatment induced rapid clinical remission and permitted complete corticosteroid withdrawal without clinical relapse.

PMID:
22874513
[PubMed - indexed for MEDLINE]
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