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Environ Toxicol. 2014 May;29(7):733-9. doi: 10.1002/tox.21799. Epub 2012 Jul 30.

Acute spill-mimicking exposure effect of hexavalent chromium on the pituitary-ovarian axis of a teleost, Channa punctatus (Bloch).

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  • 1Department of Zoology, University of Allahabad, Allahabad 211002, India.

Abstract

Acute exposure to hexavalent chromium (as 10, 20, and 40 mg/L potassium dichromate for 96 h) adversely affected the pituitary-ovarian axis of a teleost Channa punctatus. The toxic impact of metal exposure on fish ovary was revealed in the form of increased percentage of atretic follicles, significantly in 20 mg/L and 40 mg/L exposure groups. The follicular atresia mostly occurred in vitellogenic (stage II and stage III) oocytes. Reduction of serum level of 17β-estradiol was also significant in 20 mg/L and 40 mg/L exposure groups. The increase of LH-immunointensity of pituitary gonadotrophs (LHβ-immunoreactive cells) and their hypertrophy was evident, significantly in fish of 40 mg/L exposed group. Thus, the present acute metal spill-mimicking laboratory study clearly demonstrated that short-term exposures to high doses of hexavalent chromium may disrupt reproduction of the fish and affect their population.

Copyright © 2012 Wiley Periodicals, Inc., a Wiley company.

KEYWORDS:

17β-estradiol assay; Channa punctatus; acute chromium exposure effect; histopathology; immunocytochemistry; pituitary-ovarian axis

PMID:
22847992
[PubMed - in process]
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