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Case Rep Pediatr. 2012;2012:684064. doi: 10.1155/2012/684064. Epub 2012 Jul 11.

Pediatric multiple sclerosis-a challenging demyelinating disease: case report and brief review of the literature.

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  • 1Division of Neuropediatrics and Metabolic Diseases, Department of Pediatrics and Pediatric Surgery, Hospital de Base da Faculdade de Medicina de São José do Rio Preto (FAMERP), 5544 São José do Rio Preto, SP, Brazil.


Multiple sclerosis (MS) is an inflammatory, demyelinating, neurodegenerative disorder of the central nervous system (CNS) of unknown etiology. The peak onset is between age 20 and 40 years and usually affects more women than men. Although much knowledge has been achieved on the diagnosis and treatment of adult patients with MS, it remains a matter of debate and controversy in childhood. We present a case of MS in 9-year-old girl, review the current state of the knowledge on pediatric MS, and discuss the available tools for the diagnosis and treatment.

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