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Dent Clin North Am. 2012 Jul;56(3):495-520. doi: 10.1016/j.cden.2012.05.009.

Stem cell and biomaterials research in dental tissue engineering and regeneration.

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  • 1Division of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, USA.


This review summarizes approaches used in tissue engineering and regenerative medicine, with a focus on dental applications. Dental caries and periodontal disease are the most common diseases resulting in tissue loss. To replace or regenerate new tissues, various sources of stem cells have been identified such as somatic stem cells from teeth and peridontium. Advances in biomaterial sciences including microfabrication, self-assembled biomimetic peptides, and 3-dimensional printing hold great promise for whole-organ or partial tissue regeneration to replace teeth and periodontium.

Copyright © 2012 Elsevier Inc. All rights reserved.

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