Abstract
We studied the electrophysiological characteristics of systolic (SP) and diastolic (DP) potentials recorded during sinus rhythm (SR) in the left interventricular septum of a 27 year-old woman presenting with verapamil-sensitive idiopathic left ventricular tachycardia (VT). During SR, and during VT, SP was activated from ventricular base-to-apex, and DP from apex-to-base. SP and DP were both detected at the site of successful ablation during SR, whereas during VT, DP was detected away from the earliest activation site. Thus, SP apparently reflected a critical component of the reentrant circuit, while DP reflected the activation of a bystander pathway.
MeSH terms
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Action Potentials / drug effects*
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Adult
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Anti-Arrhythmia Agents / administration & dosage*
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Bystander Effect
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Catheter Ablation
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Diastole / drug effects
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Electrophysiologic Techniques, Cardiac
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Female
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Humans
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Injections, Intravenous
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Radiography, Interventional
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Systole / drug effects
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Tachycardia, Ventricular / diagnosis
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Tachycardia, Ventricular / drug therapy*
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Tachycardia, Ventricular / physiopathology
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Tachycardia, Ventricular / surgery
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Time Factors
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Treatment Outcome
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Ventricular Function, Left / drug effects*
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Ventricular Septum / drug effects*
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Ventricular Septum / physiopathology
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Ventricular Septum / surgery
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Verapamil / administration & dosage*
Substances
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Anti-Arrhythmia Agents
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Verapamil