Display Settings:

Format

Send to:

Choose Destination
Transl Biomed. 2012;3(2). pii: 2.

In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles.

Author information

  • 1Department of Neurology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

Abstract

OBJECTIVES:

The aim of this study was to determine the in vitro anti-viral effect of honey on varicella zoster virus.

METHODS:

Manuka and clover honeys were used at concentrations ranging from 0-6% wt/vol. A clinical VZV isolate was obtained from a zoster vesicle and used at low passage. Various concentrations of manuka and clover honey were added to the tissue culture medium of VZV-infected human malignant melanoma (MeWo) cells.

RESULTS:

Both types of honey showed antiviral activity against varicella zoster virus with an approximate EC50 = 4.5 % (wt/vol).

CONCLUSIONS:

Our results showed that honey has significant in vitro anti-VZV activity. As, honey is convenient for skin application, is readily available and inexpensive, honey may be an excellent remedy to treat zoster rash in developing countries where antiviral drugs are expensive or not easily available.

PMID:
22822475
[PubMed]
PMCID:
PMC3401066
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk