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Nat Immunol. 2012 Jul 19;13(8):707-12. doi: 10.1038/ni.2343.

Immunological complications of obesity.

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  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.


Current approaches for the treatment of obesity, including diet and lifestyle changes, have not been successful in curtailing the obesity epidemic. The higher incidence of inflammation-associated chronic disease and greater susceptibility to infection in obese people represents a growing health threat. Improved understanding of the immunological processes that regulate obesity may yield new treatments for obesity-associated disorders.

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