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Nat Immunol. 2012 Jul 19;13(8):707-12. doi: 10.1038/ni.2343.

Immunological complications of obesity.

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  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. thirumala-devi.kanneganti@stjude.org

Abstract

Current approaches for the treatment of obesity, including diet and lifestyle changes, have not been successful in curtailing the obesity epidemic. The higher incidence of inflammation-associated chronic disease and greater susceptibility to infection in obese people represents a growing health threat. Improved understanding of the immunological processes that regulate obesity may yield new treatments for obesity-associated disorders.

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