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Results: 20


APJ acts as a dual receptor in cardiac hypertrophy.

Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P.

Nature. 2012 Aug 16;488(7411):394-8. doi: 10.1038/nature11263.


Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.

Kim H, Scimia MC, Wilkinson D, Trelles RD, Wood MR, Bowtell D, Dillin A, Mercola M, Ronai ZA.

Mol Cell. 2011 Nov 18;44(4):532-44. doi: 10.1016/j.molcel.2011.08.045.


Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm.

Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M.

Circ Res. 2011 Aug 5;109(4):360-4. doi: 10.1161/CIRCRESAHA.111.249540. Epub 2011 Jul 7.


Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13016-21. doi: 10.1073/pnas.1120299109. Epub 2012 Jul 23.


Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.

Stojic L, Jasencakova Z, Prezioso C, Stützer A, Bodega B, Pasini D, Klingberg R, Mozzetta C, Margueron R, Puri PL, Schwarzer D, Helin K, Fischle W, Orlando V.

Epigenetics Chromatin. 2011 Sep 5;4:16. doi: 10.1186/1756-8935-4-16.


MicroRNA programs in normal and aberrant stem and progenitor cells.

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, Li L, Sage J, Zhang DE, Blau HM, Chen C, Chen CZ.

Genome Res. 2011 May;21(5):798-810. doi: 10.1101/gr.111385.110. Epub 2011 Mar 30.


Cardiac muscle regeneration: lessons from development.

Mercola M, Ruiz-Lozano P, Schneider MD.

Genes Dev. 2011 Feb 15;25(4):299-309. doi: 10.1101/gad.2018411. Review.


SIRT1 signaling as potential modulator of skeletal muscle diseases.

Tonkin J, Villarroya F, Puri PL, Vinciguerra M.

Curr Opin Pharmacol. 2012 Jun;12(3):372-6. doi: 10.1016/j.coph.2012.02.010. Epub 2012 Mar 7. Review.


Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases.

Consalvi S, Saccone V, Giordani L, Minetti G, Mozzetta C, Puri PL.

Mol Med. 2011 May-Jun;17(5-6):457-65. doi: 10.2119/molmed.2011.00049. Epub 2011 Feb 7. Review.


Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response.

Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M, Cashman JR.

J Med Chem. 2012 Jan 26;55(2):697-708. doi: 10.1021/jm2010223. Epub 2012 Jan 13.


A chemical biology approach to myocardial regeneration.

Willems E, Lanier M, Forte E, Lo F, Cashman J, Mercola M.

J Cardiovasc Transl Res. 2011 Jun;4(3):340-50. doi: 10.1007/s12265-011-9270-6. Epub 2011 Mar 22. Review.


A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis.

Cai W, Guzzo RM, Wei K, Willems E, Davidovics H, Mercola M.

Circ Res. 2012 Sep 14;111(7):876-81. doi: 10.1161/CIRCRESAHA.112.270272. Epub 2012 Aug 7.


HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.

Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F.

Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014.


Differentiation of human rhabdomyosarcoma RD cells is regulated by reciprocal, functional interactions between myostatin, p38 and extracellular regulated kinase signalling pathways.

Rossi S, Stoppani E, Puri PL, Fanzani A.

Eur J Cancer. 2011 May;47(7):1095-105. doi: 10.1016/j.ejca.2010.12.010. Epub 2011 Jan 25.


Selective control of Pax7 expression by TNF-activated p38α/polycomb repressive complex 2 (PRC2) signaling during muscle satellite cell differentiation.

Mozzetta C, Consalvi S, Saccone V, Forcales SV, Puri PL, Palacios D.

Cell Cycle. 2011 Jan 15;10(2):191-8. Epub 2011 Jan 15.


Epigenetic control of reprogramming and cellular differentiation.

Latella L, Palacios D, Forcales S, Puri PL.

Comp Funct Genomics. 2012;2012:538639. Epub 2012 Sep 17. No abstract available.


Coordination of cell cycle, DNA repair and muscle gene expression in myoblasts exposed to genotoxic stress.

Simonatto M, Giordani L, Marullo F, Minetti GC, Puri PL, Latella L.

Cell Cycle. 2011 Jul 15;10(14):2355-63. Epub 2011 Jul 15.



Caretti G, Palacios D, Sartorelli V, Puri PL.

Cell Stem Cell. 2011 Mar 4;8(3):262-5. doi: 10.1016/j.stem.2011.02.012.


Characterization of a novel angiogenic model based on stable, fluorescently labelled endothelial cell lines amenable to scale-up for high content screening.

Prigozhina NL, Heisel A, Wei K, Noberini R, Hunter EA, Calzolari D, Seldeen JR, Pasquale EB, Ruiz-Lozano P, Mercola M, Price JH.

Biol Cell. 2011 Oct 1;103(10):467-81. doi: 10.1042/BC20100146. Erratum in: Biol Cell. 2011 Dec 1;103(12):607.


An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.

Innocenzi A, Latella L, Messina G, Simonatto M, Marullo F, Berghella L, Poizat C, Shu CW, Wang JY, Puri PL, Cossu G.

EMBO Rep. 2011 Feb;12(2):164-71. doi: 10.1038/embor.2010.195. Epub 2011 Jan 7.

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