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J Gynecol Oncol. 2012 Jul;23(3):201-4. doi: 10.3802/jgo.2012.23.3.201. Epub 2012 Jul 2.

Successful term pregnancies after laparoscopic excision of poorly differentiated Sertoli-Leydig cell tumor of the ovary.

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  • 1Department of Obstetrics and Gynecology, Sultan Qaboos University Hospital, Sultan Qaboos University College of Medicine, Muscat, Sultanate of Oman.


Ovarian Sertoli-Leydig cell tumors are rare sex cord-stromal tumors, accounting for less than 1% of ovarian tumors. Majority of these tumors are benign and unilateral, only 3-5% are bilateral. These patients present with clinical features of virilization due to excessive secretion of testosterone from the tumor, however 50% may have no endocrine symptoms. We report a case of poorly differentiated Sertoli-Leydig cell tumour in a woman diagnosed during routine investigation of infertility. She had two spontaneous successful pregnancies after tumor excision laparoscopically.


Laparoscopy; Malignancy; Pregnancy; Sex-cord stromal tumor

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