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Appl Environ Microbiol. 2012 Sep;78(18):6777-80. doi: 10.1128/AEM.01678-12. Epub 2012 Jul 13.

Intestinal origin of sourdough Lactobacillus reuteri isolates as revealed by phylogenetic, genetic, and physiological analysis.

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  • 1University of Alberta, Department of Agricultural, Food and Nutritional Science, Edmonton, Alberta, Canada.


Lactobacillus reuteri is both a gut symbiont and a stable member of sourdough microbiota. This study employed multilocus sequence analysis and an analysis of host-specific physiological and genetic traits to assign five sourdough isolates to rodent- or human-specific lineages. Comparative genome hybridization revealed that the model sourdough isolate LTH2584 had a genome content very similar to that of the model rodent isolate 100-23. These results demonstrate that sourdough isolates of L. reuteri are of intestinal origin.

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