Sesquiterpene lactone glycosides from the roots of Ferula varia

Shin-ichiro Kurimoto; Kyoko Suzuki; Mamoru Okasaka; Yoshiki Kashiwada; Olimjion Kakhkharovich Kodzhimatov; Yoshihisa Takaishi

doi:10.1248/cpb.c12-00350

Sesquiterpene lactone glycosides from the roots of Ferula varia

Chem Pharm Bull (Tokyo). 2012;60(7):913-9. doi: 10.1248/cpb.c12-00350.

Authors

Shin-ichiro Kurimoto¹, Kyoko Suzuki, Mamoru Okasaka, Yoshiki Kashiwada, Olimjion Kakhkharovich Kodzhimatov, Yoshihisa Takaishi

Affiliation

¹ Graduate School of Pharmaceutical Sciences, University of Tokushima, 1–78 Shomachi, Tokushima, Japan.

PMID: 22790827
DOI: 10.1248/cpb.c12-00350

Abstract

Seven new sesquiterpene lactone glycosides (1-7) were isolated from the H2O-soluble fraction from the MeOH extract of the roots of Ferula varia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of compounds 1 and 2 were determined by modified Mosher's method.

MeSH terms

Ferula / chemistry*
Glycosides / chemistry*
Glycosides / isolation & purification
Lactones / chemistry*
Magnetic Resonance Spectroscopy
Methanol / chemistry
Molecular Conformation
Plant Roots / chemistry
Sesquiterpenes / chemistry*
Water / chemistry

Substances

Glycosides
Lactones
Sesquiterpenes
Water
Methanol