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J Occup Environ Med. 2012 Aug;54(8):1010-6. doi: 10.1097/JOM.0b013e318255ba74.

Characterization of frequency-dependent responses of the vascular system to repetitive vibration.

Author information

  • 1Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, WV 26505, USA. ksk1@cdc.gov

Abstract

OBJECTIVE:

Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves.

METHODS:

The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured.

RESULTS:

Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz.

CONCLUSION:

Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.

PMID:
22785326
[PubMed - indexed for MEDLINE]
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