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BMC Syst Biol. 2011;5 Suppl 3:S6. doi: 10.1186/1752-0509-5-S3-S6. Epub 2011 Dec 23.

Mass segmentation using a combined method for cancer detection.

Author information

  • 1College of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, Hubei, China.

Abstract

BACKGROUND:

Breast cancer is one of the leading causes of cancer death for women all over the world and mammography is thought of as one of the main tools for early detection of breast cancer. In order to detect the breast cancer, computer aided technology has been introduced. In computer aided cancer detection, the detection and segmentation of mass are very important. The shape of mass can be used as one of the factors to determine whether the mass is malignant or benign. However, many of the current methods are semi-automatic. In this paper, we investigate fully automatic segmentation method.

RESULTS:

In this paper, a new mass segmentation algorithm is proposed. In the proposed algorithm, a fully automatic marker-controlled watershed transform is proposed to segment the mass region roughly, and then a level set is used to refine the segmentation. For over-segmentation caused by watershed, we also investigated different noise reduction technologies. Images from DDSM were used in the experiments and the results show that the new algorithm can improve the accuracy of mass segmentation.

CONCLUSIONS:

The new algorithm combines the advantages of both methods. The combination of the watershed based segmentation and level set method can improve the efficiency of the segmentation. Besides, the introduction of noise reduction technologies can reduce over-segmentation.

PMID:
22784625
[PubMed - indexed for MEDLINE]
PMCID:
PMC3287574
Free PMC Article
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