Send to:

Choose Destination
See comment in PubMed Commons below
Cell Stem Cell. 2012 Jul 6;11(1):3-4. doi: 10.1016/j.stem.2012.06.014.

Reprogramming a broken heart.

Author information

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.


Fibrosis resulting from cardiac injury presents a major challenge to restoring heart function after myocardial infarction. Two recent papers in Nature report successful in vivo reprogramming of fibroblasts to cardiomyocytes in injured mouse hearts (Qian et al., 2012; Song et al., 2012), resulting in improved cardiac function and reduced scar formation.

Copyright © 2012 Elsevier Inc. All rights reserved.

Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk