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Oncoimmunology. 2012 May 1;1(3):346-350.

Revisiting the role of T cells in tumor regression.

Author information

  • 1Inserm; U1016; Institut Cochin; Paris, France ; CNRS; UMR8104; Paris, France ; Univ Paris Descartes; Paris, France.

Abstract

This note challenges the current idea that a key role of T cells in tumor regression is to directly kill tumor cells. It favors the view that TIL are keys but act indirectly by helping other immune cells to damage the tumor and its stroma.

PMID:
22737611
[PubMed]
PMCID:
PMC3382877
Free PMC Article
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