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Intern Med. 2012;51(12):1619-21. Epub 2012 Jun 15.

Infectious endocarditis caused by Lactobacillus acidophilus in a patient with mistreated dental caries.

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  • 1AIDS Clinical Center, National Center for Global Health and Medicine, Japan.


We present a rare case of infectious endocarditis caused by Lactobacillus acidophilus in a patient on long-term steroid use for autoimmune hepatitis. In vitro susceptibility-guided antibiotics with benzylpenicillin plus clindamycin and successive mitral annuloplasty resulted in a favorable outcome. Infectious endocarditis was suspected to be a complication of mistreated periodontal infection. Maintenance of oral hygiene is important in immunocompromised patients.

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