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Fertil Steril. 2012 Aug;98(2):251-2. doi: 10.1016/j.fertnstert.2012.05.011. Epub 2012 Jun 20.

Klinefelter syndrome: how, what, and why?

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  • Division of Urology, Brown University and Rhode Island Hospital, Providence, Rhode Island 02905, USA. Mark_Sigman@Brown.edu


Klinefelter syndrome is commonly encountered by the physician dealing with male infertility. Despite the success of sperm retrieval and ICSI, there remain many areas of controversy about the mechanisms and natural history of spermatogenesis, as well as the appropriate management of these patients. This collection of articles provides a state of the art review of what is known and what is unknown about this syndrome and reports a variety of management approaches to these patients.

Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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