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Chem Biol. 2012 Jun 22;19(6):660-1. doi: 10.1016/j.chembiol.2012.06.003.

Malarial parasites accumulate labile zinc pools.

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  • Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 56-341b, Cambridge, MA 02139, USA. jcniles@mit.edu

Abstract

The malarial parasite, Plasmodium falciparum, is an intracellular pathogen and partially dependent on nutrient uptake for survival. In this issue of Chemistry & Biology, Marvin et al. demonstrate that zinc is essential for parasite growth and that the parasite maintains substantial labile cytosolic and mitochondrial zinc pools.

Copyright © 2012 Elsevier Ltd. All rights reserved.

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PMID:
22726676
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