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Cardiol Young. 2012 Oct;22(5):493-8. doi: 10.1017/S1047951112000492. Epub 2012 Apr 16.

Surgical repair of atrial septal defect with severe pulmonary hypertension during pregnancy: a case report with literature review.

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  • 1Department of Medicine, University of South Florida, Tampa, Florida, United States of America.


We are reporting a case of a 37-year-old pregnant woman with a large secundum atrial septal defect with left-to-right shunt and severe pulmonary hypertension. Her atrial septal defect was undiagnosed before this pregnancy. After carefully considering all the options, we repaired her atrial septal defect with an open heart surgical closure at 20 weeks of gestation. A substantial and consistent reduction in pulmonary arterial pressure after the surgery and subsequent uneventful delivery indicate that surgical repair of atrial septal defects is a viable option that should be considered for such patients.

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