Display Settings:

Format

Send to:

Choose Destination
Behav Neurol. 2013;26(1-2):21-34. doi: 10.3233/BEN-2012-110237.

Patterns of dysgraphia in primary progressive aphasia compared to post-stroke aphasia.

Author information

  • 1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Abstract

We report patterns of dysgraphia in participants with primary progressive aphasia that can be explained by assuming disruption of one or more cognitive processes or representations in the complex process of spelling. These patterns are compared to those described in participants with focal lesions (stroke). Using structural imaging techniques, we found that damage to the left extrasylvian regions, including the uncinate, inferior fronto-occipital fasciculus, and sagittal stratum (including geniculostriate pathway and inferior longitudinal fasciculus), as well as other deep white and grey matter structures, was significantly associated with impairments in access to orthographic word forms and semantics (with reliance on phonology-to-orthography to produce a plausible spelling in the spelling to dictation task). These results contribute not only to our understanding of the patterns of dysgraphia following acquired brain damage but also the neural substrates underlying spelling.

PMID:
22713396
[PubMed - indexed for MEDLINE]
PMCID:
PMC3620674
Free PMC Article

Images from this publication.See all images (5)Free text

Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for IOS Press Icon for PubMed Central
    Loading ...
    Write to the Help Desk