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Colorectal Dis. 2012 Oct;14(10):e740-6. doi: 10.1111/j.1463-1318.2012.03132.x.

Clinical associations and risk factors for bleeding from colonic angiectasia: a case-controlled study.

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  • 1Gastroenterology Division Department of Medical Education, Yokohama City University School of Medicine, Yokohama, Japan.

Abstract

AIM:

A case-controlled study was performed to investigate the association of colonic angiectasia with other conditions and to identify risk factors for bleeding.

METHOD:

Information was collected from all patients who underwent colonoscopy at our hospital between January 2008 and December 2010. Data on 90 individuals with angiectasia [58 men; median age 69 (26-92) years] were compared with those of 180 individuals without angiectasia, matched for gender and age.

RESULTS:

Multivariate analysis showed that occult gastrointestinal bleeding [odds ratio (OR) 2.523; 95% confidence interval (CI) 1.238-5.142], liver cirrhosis (OR 13.195; 95% CI 3.502-49.711), chronic renal failure (OR 6.796; 95% CI 1.598-28.904) and valvular heart disease (OR 6.425; 95% CI 1.028-40.165) were identified as significant predictors of the presence of colonic angiectasia. Eight patients were diagnosed with bleeding from angiectasia. Cardiovascular disease (OR 22.047; 95% CI 1.063-457.345) and multiple angiectasias (P-value 0.0019) were identified as significant risk factors for active bleeding. Medication and a large size were not associated with an increased risk of bleeding.

CONCLUSION:

The presence of colonic angiectasia was associated with valvular heart disease, liver cirrhosis and chronic renal failure. Valvular heart disease and multiple lesions increased the risk of bleeding.

© 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.

PMID:
22709354
[PubMed - indexed for MEDLINE]
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