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Psychiatry Investig. 2012 Jun;9(2):127-33. doi: 10.4306/pi.2012.9.2.127. Epub 2012 Apr 2.

Determinants of quality of life in the acute stage following stroke.

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  • 1Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.

Abstract

OBJECTIVE:

This study aimed to investigate the factors influence the quality of life (QOL) of survivors of an acute stroke.

METHODS:

For 422 stroke patients, assessments were made within two weeks of the index event. QOL was measured using the World Health Organization Quality of Life-Abbreviated form (WHOQOL-BREF), which has four domains related to physical factors, psychological factors, social relationships, and environmental context. Associations of each four WHOQOL-BREF domain score with socio-demographic characteristics (age, sex, education, marital status, religion, and occupation), stroke severity (National Institutes of Health Stroke Scale), physical disability (Barthel Index), cognitive function (Mini-Mental Status Examination: MMSE), grip strength, and psychological distress (Hospital Anxiety and Depression Scale depression and anxiety subscale: HADS-D and HADS-A) were investigated using the linear regression models.

RESULTS:

Higher physical domain scores were independently associated with higher MMSE scores, stronger hand-grip strength, and lower HADS-D and HADS-A scores; higher psychological domain scores were independently associated with higher educational level, higher MMSE scores, and lower HADS-D and HADS-A scores; higher social relationships domain scores were independently associated with lower HADS-D and HADS-A scores; and higher environmental domain scores were independently associated with higher educational level, higher MMSE scores, and lower HADS-D scores.

CONCLUSION:

Psychological distress and impaired cognitive function were independently associated with lower QOL in patients with acute stroke. However, stroke severity, physical disability and other socio-demographic factors were less significantly associated with QOL. These findings underscore the importance of psychological interventions for improving QOL during the acute phase following stroke.

KEYWORDS:

Anxiety; Cognitive function; Depression; Quality of life; Stroke

PMID:
22707962
[PubMed]
PMCID:
PMC3372559
Free PMC Article
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