¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form

Cuiping Fu; Yu Peng; Xinli Liao; Chenyun Guo; Donghai Lin

doi:10.1007/s12104-012-9399-5

¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form

Biomol NMR Assign. 2013 Oct;7(2):155-8. doi: 10.1007/s12104-012-9399-5. Epub 2012 Jun 17.

Authors

Cuiping Fu¹, Yu Peng, Xinli Liao, Chenyun Guo, Donghai Lin

Affiliation

¹ The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.

PMID: 22706932
DOI: 10.1007/s12104-012-9399-5

Abstract

AK1 (Adenylate Kinase 1) plays crucial roles in processes such as cellular phosphotransfer networks, neuronal maturation and regeneration, gating of ABC transporter CFTR, tumor cell metabolism and myocardial energetic homeostasis. Here we report (1)H, (15)N and (13)C backbone and side-chain resonance assignments of the human AK1 protein in apo form. This work lays the essential basis for the further structure determination of hAK1.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenylate Kinase / chemistry*
Apoenzymes / chemistry*
Carbon Isotopes
Humans
Nitrogen Isotopes
Nuclear Magnetic Resonance, Biomolecular*
Protein Structure, Secondary
Protons*

Substances

Apoenzymes
Carbon Isotopes
Nitrogen Isotopes
Protons
Adenylate Kinase
adenylate kinase 1