Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Expert Rev Mol Diagn. 2012 Jun;12(5):437-43. doi: 10.1586/erm.12.34.

Near instrument-free, simple molecular device for rapid detection of herpes simplex viruses.

Author information

  • 1BioHelix Corporation, 500 Cummings Center, Suite 5550, Beverly, MA 01915, USA.

Abstract

The first near instrument-free, inexpensive and simple molecular diagnostic device (IsoAmp HSV, BioHelix Corp., MA, USA) recently received US FDA clearance for use in the detection of herpes simplex viruses (HSV) in genital and oral lesion specimens. The IsoAmp HSV assay uses isothermal helicase-dependent amplification in combination with a disposable, hermetically-sealed, vertical-flow strip identification. The IsoAmp HSV assay has a total test-to-result time of less than 1.5 h by omitting the time-consuming nucleic acid extraction. The diagnostic sensitivity and specificity are comparable to PCR and are superior to culture-based methods. The near instrument-free, rapid and simple characteristics of the IsoAmp HSV assay make it potentially suitable for point-of-care testing.

PMID:
22702360
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Informa Healthcare
    Loading ...
    Write to the Help Desk