Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Fitoterapia. 2012 Sep;83(6):1008-13. doi: 10.1016/j.fitote.2012.06.001. Epub 2012 Jun 11.

Tyrosinase inhibition constituents from the roots of Morus australis.

Author information

  • 1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, PR China.

Abstract

The phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents.

Copyright © 2012 Elsevier B.V. All rights reserved.

PMID:
22698714
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk