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BMJ Case Rep. 2011 Apr 19;2011. pii: bcr1120103509. doi: 10.1136/bcr.11.2010.3509.

Caudal clonidine-bupivicaine block with bladder hydrodistension: a novel combined treatment for the painful bladder.

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  • 1Department of Urology, Royal Berkshire Hospital, Reading, UK.


The authors describe a new combination procedure consisting of bladder hydrodistension with clonidine-bupivicaine caudal block for the symptomatic relief of bladder pain. They report this new technique whereby patients who had tried multiple forms of therapy with little response, including bladder hydrodistension under general anaesthesia for their chronic pelvic bladder pain, responded to this novel combination therapy.

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