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Chimerism. 2012 Jan-Mar;3(1):18-20.

Fetal-maternal interface: a chronicle of allogeneic coexistence.

Author information

  • 1ICREC Research Group, Health Sciences Research Institute Germans Trias i Pujol, Barcelona, Spain.

Abstract

The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child's cells within the mother's blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models.

KEYWORDS:

fetal-maternal interface; fish; microchimerism; placenta; tolerance

PMID:
22690268
[PubMed - indexed for MEDLINE]
PMCID:
PMC3370925
Free PMC Article

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