(*A*) Comparison of the correlation coefficient *R* between the trajectories *γ*_{n}(*t*) and *δ*_{n}(*t*) (filled symbols) and between the steps Δ*γ*_{n}(*t*) and Δ*δ*_{n}(*t*) (empty symbols) along the amino acid sequence of VA3. The α-helices and β-sheets are indicated by light gray and dark gray stripes, respectively. The full horizontal lines represent *R* averaged over the primary sequence (*R*_{avg}) for the steps (lowest) and for the trajectories (highest). The dashed line represents the value *R*_{avg} + *σ* = 0.85 for the trajectories. (*B*) Maximum (squares), average (diamonds), and minimum (triangles) values over the amino acid sequence of the correlation coefficient *R*_{n}(*M*) between the displacements Δ*γ*_{n}(*t*; *M*) and Δ*δ*_{n}(*t*; *M*) as function of the logarithm of the number *M* of steps. The value of *R*_{n}(*M*) was computed for *M* equals to 1, 10, 30, 100, 500, 1,000, 2,000, and 10,000. The values of *R*_{max}, *R*_{avg} and *R*_{min} computed between the *γ*_{n}(*t*) and *δ*_{n}(*t*) trajectories are shown for comparison (circles) at *M* = 10,000. All calculations were performed from the five MD runs (over 400 ns).

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