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Pediatr Pulmonol. 2012 Jul;47(7):722-6. doi: 10.1002/ppul.21611. Epub 2012 Jan 3.

Invasive pneumonia and septic shock in infants as a presentation of cystic fibrosis with vitamin-deficiency.

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  • 1Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. enfantsdoc@gmail.com

Abstract

Herein we describe three infants with the rare presentation of pneumonia with septic shock as their initial medical encounter leading to the diagnosis of cystic fibrosis (CF). At the time of their presentation all three children had significant nutritional deficiency. We initiated an aggressive treatment regimen including nutritional supplementation which resulted in improvement in their pulmonary status and no further recurrences. This series highlights the possible presentation of CF in infancy as a life-threatening invasive infection of Staphylococcus aureus or Pseudomonas aeruginosa. It also supports neonatal screening and emphasizes the role of early attention to nutritional status and vitamin supplementation.

Copyright © 2011 Wiley Periodicals, Inc.

PMID:
22684986
[PubMed - indexed for MEDLINE]
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