Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Cell Biol. 2012 Aug;24(4):541-6. doi: 10.1016/j.ceb.2012.05.005. Epub 2012 Jun 8.

Centrosome asymmetry and inheritance during animal development.

Author information

  • 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada. pelletier@lunenfeld.ca

Abstract

The centrosome is a subcellular organelle that is responsible for the majority of microtubule organization. Through this ability, the centrosome is involved in cell division, migration, and polarization. Recent studies have revealed intriguing asymmetries between mother and daughter centrioles as well as between mother and daughter centrosomes, and the involvement of such asymmetries in multiple cellular and developmental processes. This review aims to summarize recent discoveries on such asymmetries in centrioles/centrosomes and the potential implication of their inheritance patterns during cell division and development.

Copyright © 2012 Elsevier Ltd. All rights reserved.

PMID:
22683192
[PubMed - indexed for MEDLINE]
PMCID:
PMC3425708
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk