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Anal Biochem. 2012 Sep 1;428(1):4-6. doi: 10.1016/j.ab.2012.05.025. Epub 2012 Jun 4.

Synthesis of NaYF(4):Yb,Er/single-walled carbon nanohorns nanocomposite and its application as cells label.

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  • 1Department of Chemistry, Northeastern University, Shenyang 110819, China.


A novel nanocomposite synthesis method of amino-modified NaYF(4):Yb,Er upconversion luminescent nanoparticles and single-walled carbon nanohorns was developed via covalent linkage for the first time. The nanocomposite was covalently coupled with rabbit anti-CEA8 antibody and then used successfully as a cell labeling agent for the immunolabeling and imaging of HeLa cells.

Copyright © 2012 Elsevier Inc. All rights reserved.

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