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N Am J Med Sci. 2009 Dec;1(7):377-80. doi: 10.4297/najms.2009.7377.

Familial early onset of type-2 diabetes mellitus and its complications.

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  • 1Diabetes Centre & Department of Medicine, K.L.E.S Dr. Prabhakar Kore Hospital & Medical Research Centre & Jawaharlal Nehru Medical College, KLE University, Belgaum- 590010, Karnataka, India.



Globally, the prevalence of chronic, non-communicable diseases is increasing at an alarming rate. Furthermore, approximately 197 million people worldwide have impaired glucose tolerance. Consequently, diabetes is rapidly emerging as a global health problem that threatens to assume a pandemic level by 2030. In Indian population, genetic predisposition to trigger diabetes at an early age as compared to western counterpart has been focused very much.


To gain further insight into the positive correlation between the diabetes and family history was the objective of this study.


Patients attending the Diabetes Centre, K.L.E.S Dr. Prabhakar. Kore Hospital and Medical Research Centre; J. N. Medical College; KLE University Belgaum, Karnataka- India, were recruited, diagnosed and analyzed as per WHO criteria.


The prevalence of diabetes was higher among patients with diabetic mother (25.6%) compared to patients with diabetic father (21.2%) and there was early onset of type -2 diabetes among patients having both parents with diabetic when compared to other patients.


Based on the present observation, it would be appropriate to emphasize again that a strong family history for diabetes, would signal at an early age, the onset of diabetes perhaps with its complications.


Family history; nephropathy.; retinopathy; type-2 diabetes mellitus

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