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N Am J Med Sci. 2009 Dec;1(7):377-80. doi: 10.4297/najms.2009.7377.

Familial early onset of type-2 diabetes mellitus and its complications.

Author information

  • 1Diabetes Centre & Department of Medicine, K.L.E.S Dr. Prabhakar Kore Hospital & Medical Research Centre & Jawaharlal Nehru Medical College, KLE University, Belgaum- 590010, Karnataka, India.

Abstract

BACKGROUND:

Globally, the prevalence of chronic, non-communicable diseases is increasing at an alarming rate. Furthermore, approximately 197 million people worldwide have impaired glucose tolerance. Consequently, diabetes is rapidly emerging as a global health problem that threatens to assume a pandemic level by 2030. In Indian population, genetic predisposition to trigger diabetes at an early age as compared to western counterpart has been focused very much.

AIM:

To gain further insight into the positive correlation between the diabetes and family history was the objective of this study.

MATERIALS AND METHODS:

Patients attending the Diabetes Centre, K.L.E.S Dr. Prabhakar. Kore Hospital and Medical Research Centre; J. N. Medical College; KLE University Belgaum, Karnataka- India, were recruited, diagnosed and analyzed as per WHO criteria.

RESULTS:

The prevalence of diabetes was higher among patients with diabetic mother (25.6%) compared to patients with diabetic father (21.2%) and there was early onset of type -2 diabetes among patients having both parents with diabetic when compared to other patients.

CONCLUSION:

Based on the present observation, it would be appropriate to emphasize again that a strong family history for diabetes, would signal at an early age, the onset of diabetes perhaps with its complications.

KEYWORDS:

Family history; nephropathy.; retinopathy; type-2 diabetes mellitus

PMID:
22666728
[PubMed]
PMCID:
PMC3364686
Free PMC Article
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