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ScientificWorldJournal. 2012;2012:930139. doi: 10.1100/2012/930139. Epub 2012 May 1.

Lipids and all-cause mortality among older adults: a 12-year follow-up study.

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  • 1Postgraduate Program in Public Health, State University of Londrina-UEL, Robert Koch Avenue, 60 CEP, 86038440 Londrina, PR, Brazil.


This is a 12-year follow-up cohort study with 800 people (60-85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170 mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50. An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20 kg/m² or mortality in ≤ 2 years. The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c. After the exclusion of underweight and premature mortality, there was a positive association only with TC <170 mg/dl (HR = 1.36, CI95%: 1.02-1.82). The data did not show a higher risk with high levels of TC, LDL-c, and TG. However, they showed higher mortality among older adults with low TC.

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