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BMJ Case Rep. 2012 Feb 25;2012. pii: bcr1020115044. doi: 10.1136/bcr.10.2011.5044.

Triple negative mixed metaplastic breast carcinoma with squamous and spindle cells in an 84-year-old woman: a rare entity with unclear management strategy and poor prognosis.

Author information

  • 1Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA. srujitha.murukutla@gmail.com

Abstract

Metaplastic carcinoma of the breast, a rare neoplasm, usually presents at an advanced stage, metastasises to distant sites more frequently, has higher Ki-67 expression and is more often triple negative compared with other invasive breast cancers. Here, the authors discuss a case of an 84-year-old woman with triple negative mixed metaplastic breast carcinoma treated with radical modified mastectomy, axillary lymph node dissection and radiation therapy. Because of the rarity of the disease, the pathogenesis and the management remain controversial, thus contributing to overall poor prognosis.

PMID:
22665553
[PubMed - indexed for MEDLINE]
PMCID:
PMC3291009
Free PMC Article

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