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Handb Clin Neurol. 2012;106:9-35. doi: 10.1016/B978-0-444-52002-9.00002-4.

Receptor signaling and the cell biology of synaptic transmission.

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  • 1Department of Physiology, University of Illinois, Chicago, IL, USA.


This volume describes a series of psychiatric and neuropsychiatric disorders, connects some aspects of somatic and psychiatric medicine, and describes various current and emerging therapies. The purpose of this chapter is to set the stage for the volume by developing the theoretical basis of synaptic transmission and introducing the various neurotransmitters and their receptors involved in the process. The intent is to provide not only a historical context through which to understand neurotransmitters, but a current contextual basis for understanding neuronal signal transduction and applying this knowledge to facilitate treatment of maladies of the brain and mind.

Copyright © 2012 Elsevier B.V. All rights reserved.

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