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J Asian Nat Prod Res. 2012;14(6):607-11. doi: 10.1080/10286020.2012.674944.

A new triterpenoid saponin from Sanguisorba officinalis.

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  • 1Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China.


A new 19-oxo-18,19-seco-ursane-type triterpenoid saponin, named sanguisoside A (1), along with nine known triterpenoid saponins (2-10), was isolated from the roots of Sanguisorba officinalis. Their structures were determined on the basis of spectroscopic analysis and chemical method. Compounds 2 and 3 showed cytotoxic activity against SGC-7901, SMMC-7721, A549, and DU145 cell lines.

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