Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Indian J Dermatol Venereol Leprol. 2012 May-Jun;78(3):290-8. doi: 10.4103/0378-6323.95443.

Role of nail biopsy as a diagnostic tool.

Author information

  • 1Department of Dermatology, Venereology and Leprology, University College of Medical Sciences, Delhi, India. chandergroverkubba@rediffmail.com


Nail biopsy (NB) is an investigation that is not routinely resorted to by most of the dermatologists. The commonly cited reasons are the complexity of the procedure, risk of scarring and the reluctance of the patient. However, in cases with isolated nail psoriasis, isolated nail lichen planus, onychomycosis not confirmed on direct microscopy and culture, or longitudinal melanonychia, the treating dermatologist is left with no choice but to resort to this procedure. Nail as a unit, is capable of projecting only a limited number of clinical manifestations. This is responsible for the more or less similar clinical presentation of many different nail disorders. Hence, a practical knowledge of the indications, appropriate patient selection, procedural details and histopathological interpretation of a NB is a must-have for any practicing dermatologist. The risk of scarring is none to minimal if appropriate type of biopsy is performed, not to mention the wealth of histopathological data that can be retrieved from the nail unit. This article aims to explore the various practical do's and don'ts for the NB and tells us what to expect from of the procedure.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Icon for Medknow Publications and Media Pvt Ltd
    Loading ...
    Write to the Help Desk