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Respir Investig. 2012 Mar;50(1):14-22. doi: 10.1016/j.resinv.2012.02.002. Epub 2012 Mar 10.

Nationwide survey on the 2005 Guidelines for the Management of Community-Acquired Adult Pneumonia: validation of severity assessment.

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  • 1Institute of Development, Aging and Cancer, Tohoku University, Research Division for Development of Anti-Infective Agents, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Miyagi, Japan. akiwa@idac.tohoku.ac.jp

Abstract

INTRODUCTION:

The Japanese Respiratory Society Guidelines for the Management of Community-Acquired Pneumonia (CAP) in Adults (JRS 2005) were published to revise the Basic Concept for the Management of CAP in Adults (JRS 2000). Revisions in JRS 2005 mainly focused on the criteria for the assessment of pneumonia severity and the differentiation between bacterial pneumonia and atypical pneumonia. To evaluate the JRS 2005 criteria for the assessment of pneumonia severity, we conducted a prospective survey.

SUBJECTS AND METHODS:

The survey was conducted from July 2006 to March 2007 as a nationwide joint study by 200 institutions. The study subjects included patients aged ≥16 years of age who had CAP. The severity at initial consultation was determined using the criteria established by JRS 2005, JRS 2000, and Infectious Diseases Society of America Guidelines (IDSA-GLs). The survival outcome 30 days after the start of the initial antimicrobial agent treatment was confirmed.

RESULTS:

A total of 1875 patients were analyzed. The numbers of cases of pneumonia assessed as being moderate and severe were significantly lower when the JRS 2005 criteria were used than when the JRS 2000 criteria were used. Thus, the severity of pneumonia could be determined more appropriately using the JRS 2005 criteria. Furthermore, the severity-dependent prediction of fatal outcomes or mortality according to these criteria was similar to that determined using the IDSA-GLs.

CONCLUSIONS:

Determining severity on the basis of JRS 2005 can resolve nearly all the problems encountered with JRS 2000; these criteria were found to be useful and rapidly and easily applicable in clinical practice.

Copyright © 2012 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

PMID:
22554855
[PubMed - indexed for MEDLINE]
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