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Gynecol Endocrinol. 2012 Jul;28(7):533-5. doi: 10.3109/09513590.2011.632789. Epub 2012 May 2.

Cushing disease with pregnancy.

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  • 1Department of Endocrinology, KEM Hospital, Mumbai, India.


Pregnancy occurs rarely in patients with Cushing syndrome (CS) due to hypercortisolism. So far, about 150 cases of CS in pregnancy have been reported in the literature. We describe a 22-year-old female who presented in pregnancy with clinical features of CS. She delivered at 34 weeks of gestation and baby had transient adrenal insufficiency in the neonatal period. Mother underwent transsphenoidal surgery 1 year postpartum and on follow up she is under remission. Neonatal hypoadrenalism should be anticipated in maternal CS.

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