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Clin Calcium. 2012 May;22(5):736-9. doi: CliCa1205736739.

[Is calcium supplement useful in aged persons? Calcium supplement doesn't reduce the fracture and vascular risk in aged persons].

[Article in Japanese]

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  • 1Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Japan.


Although there are biologically plausible mechanisms by which calcium supplements reduce bone loss and lower rate of vertebral fracture in older persons, recent studies failed to demonstrate the effects of calcium supplements to reduce fracture risk. In addition, either observational or interventional studies showed that calcium supplements were associated with increase in myocardial infarction. Taken together, the reassessment of the role of calcium supplements for the prevention of osteoporosis and fracture should be warranted.

[PubMed - indexed for MEDLINE]
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