Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Physiol Behav. 2012 Nov 5;107(4):540-52. doi: 10.1016/j.physbeh.2012.04.011. Epub 2012 Apr 17.

Flavor is in the brain.

Author information

  • 1The John B Pierce Laboratory, 290 Congress Avenue, New Haven, CT, USA. dsmalll@jbpierce.org

Abstract

Flavor is perhaps the most multi-modal of all of our sensory experiences. Here flavor is defined as a perception that includes gustatory, oral-somatosensory, and retronasal olfactory signals that arise from the mouth as foods and beverages are consumed. Although the sights, sounds and smells of foods that occur just before, or in the absence of eating, can impact flavor perception, it is argued that these sensory signals exert their influence by creating expectations based upon prior associations. The primary aim of the paper is to review anatomical and neurophysiological data towards an understanding of how the core sensory signals combine in the central nervous system of humans. Based upon the extant literature it is proposed that taste, oral-somatosensory and olfactory inputs are first integrated in the anterior ventral insula. The core flavor percept is then conveyed to upstream regions in the brainstem and thalamus, as well as downstream regions in the amygdala, orbitofrontal cortex and anterior cingulate cortex to produce the rich flavorful experiences that guide our feeding behavior.

Copyright © 2012 Elsevier Inc. All rights reserved.

PMID:
22542991
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk