The human corticosteroid binding globulin gene is ...[Hum Genet. 1990]

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1: Hum Genet. 1990 Nov;86(1):73-5.Links

The human corticosteroid binding globulin gene is located on chromosome 14q31-q32.1 near two other serine protease inhibitor genes.

Seralini GE, Bérubé D, Gagné R, Hammond GL.

Department of Obstetrics and Gynecology, University of Western Ontario, London, Canada.

Human corticosteroid binding globulin (CBG) cDNA fragments were radiolabeled and hybridized in situ to metaphase chromosome preparations. The results localized the CBG gene to the q31-q32.1 region of human chromosome 14. This location also contains the genes for two closely related serine protease inhibitors: alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin. It is therefore likely that these genes evolved by duplication events, and it would appear that this region contains a series of functionally related genes.

PMID: 2253941 [PubMed - indexed for MEDLINE]

A 370-kb cosmid contig of the serpin gene cluster on human chromosome 14q32.1: molecular linkage of the genes encoding alpha 1-antichymotrypsin, protein C inhibitor, kallistatin, alpha 1-antitrypsin, and corticosteroid-binding globulin.
Genomics. 1997 Dec 15; 46(3):409-15.

[Genomics. 1997]
Physical mapping of four serpin genes: alpha 1-antitrypsin, alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome I4q32.1.
Am J Hum Genet. 1993 Feb; 52(2):343-53.

[Am J Hum Genet. 1993]
Molecular linkage of the human alpha 1-antitrypsin and corticosteroid-binding globulin genes on chromosome 14q32.1.
Mamm Genome. 1997 Dec; 8(12):913-6.

[Mamm Genome. 1997]
ReviewMolecular studies of corticosteroid binding globulin structure, biosynthesis and function.
J Steroid Biochem Mol Biol. 1991; 40(4-6):755-62.

[J Steroid Biochem Mol Biol. 1991]
ReviewA review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.
Genomics. 2003 Mar; 81(3):336-45.

[Genomics. 2003]
» See reviews... | » See all...

Cited by 2 PubMed Central articles

ReviewSingle gene disorders affecting the gastrointestinal tract.
Taylor GR, Farmery SM. Gut. 1993 Apr; 34(4):433-6.

[Gut. 1993]
Physical mapping of four serpin genes: alpha 1-antitrypsin, alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome I4q32.1.
Billingsley GD, Walter MA, Hammond GL, Cox DW. Am J Hum Genet. 1993 Feb; 52(2):343-53.

[Am J Hum Genet. 1993]

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The human corticosteroid binding globulin gene is located on chromosome 14q31-q32.1 near two other serine protease inhibitor genes.

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Cited by 2 PubMed Central articles

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